![]() Here we discuss how host–gene–microbial interactions are major determinants for the development of these multifactorial chronic disordersĨ7 Reprinted from Cell 147(1), Virgin, H. It contributes the majority of genetic information to our metagenome and, consequently, influences our resistance and susceptibility to diseases, especially common inflammatory diseases, such as type 1 diabetes, ulcerative colitis, and Crohn’s disease. The microbiome is a complex community of Bacteria, Archaea, Eukarya, and viruses that infect humans and live in our tissues. ![]() METAGENOMICS AND PERSONALIZED MEDICINE 87 A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Dectin-1 is required for beta-glucan recognition and control of fungal infection. ![]() A comparison of bayesian methods for haplotype reconstruction from population genotype data. A new statistical method for haplotype reconstruction from population data. Novel anti-glycan antibodies related to inflammatory bowel disease diagnosis and phenotype. ![]() Abundant and diverse fungal microbiota in the murine intestine. ![]() Team R: A Language and Environment for Statistical Computing. A human gut microbial gene catalogue established by metagenomic sequencing. Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. ![]()
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